Contraindications for ciprofloxacin


The most common side effects of this medicine are gastrointestinal symptoms, that often are mild and transient.

Particular attention should be paid to its adverse effects on the central nervous system and tendons while being treated with this medicinal product.

In clinical reserches, ciprofloxacin was associated with neurotoxicity and may cause partial epileptic status. It can also affect the mental state and cause confusion. The mechanism by which ciprofloxacin leads to the adverse effects of the CNS is not yet known.

In the FDA recommendations pay attention on use of fluoroquinolone antibiotics only in case of last resort because it may lead to permanent peripheral neuropathy.

Due to their efficiency and pressure from patients to resolve the infection as fast as possible, doctors, unfortunately, often prescribe these antibiotics despite their risks

However, it should be noted that most patients only experience mild CNS side effects, such as headache and drowsiness.

For the above reasons, ciprofloxacin should not be used in patients who have or have had neuropathy, anxiety, depression, anxiety, epilepsy, obsessive-compulsive disorder and other CNS disorders.

Fluoroquinolones can cause tendonitis (inflammation and tendon rupture) in approximately 0.15 to 0.40% of patients taking these antibiotics. Tendonitis can affect tendons in the hands or the Achilles tendon, shoulders and glutes. If you notice muscle pain, swelling, contact your doctor immediately. The risk of tendonitis is greater in the elderly.

Therefore, ciprofloxacin should not be used in patients who already have muscle problems.

Ciprofloxacin, pregnancy and lactation

The FDA classification has placed Ciprofloxacin in group C (the risk has been demonstrated in animals, but there are no studies in humans).

Since urinary tract infection is a common complication during pregnancy, it should be treated.
One study reported that ciprofloxacin does not cause malformations but should not be used as a first-line drug for the treatment of urinary tract infections during pregnancy. Other study examined 200 pregnant women to find out if this drug has adverse effects on the musculoskeletal system of the fetus. The connection between adverse effects and this drug was not established.

It is excreted in breast milk and breastfeeding should be avoided.


The dose and duration of treatment depend on the severity of the infection, the infection type, the patient’s age, the patient’s body weight, and the patient’s renal function.

Your health-care doctor should determine the appropriate dose of Cipro for you.

The usual dosage regimen involves the use of this medication twice a day.

It can be taken with or without food, but you should avoid the simultaneous use of dairy products with this medicine.